Ann Rheum Dis. 1992 Mar;51(3):303-6.

Food intolerance in rheumatoid arthritis. II. Clinical and histological aspects.

van de Laar MA, Aalbers M, Bruins FG, van Dinther-Janssen AC, van der Korst JK, Meijer CJ.

Source

Department of Rheumatology, Jan van Breemen Instituut and Academisch Medisch Centrum, University of Amsterdam, The Netherlands.

Abstract

Six patients with rheumatoid factor positive rheumatoid arthritis who had shown a marked symptomatic improvement during four weeks of hypoallergic, artificial diet were studied in greater detail. Placebo controlled rechallenges showed intolerance for specific foodstuffs in four patients. In three of these patients biopsies of both the synovial membrane and of the proximal small intestine were carried out before and during allergen free feeding. In two patients, both with raised serum IgE concentrations and specific IgE antibodies to certain foods, a marked reduction of mast cells in the synovial membrane and proximal small intestine was demonstrated. Although the number of food intolerant patients with RA remains limited and markers of allergic activity are scanty, our observations suggest an underlying immunoallergological mechanism.

Comment in

Ann Rheum Dis. 1993 Jan;52(1):88.

PMID:: 1575572; [PubMed - indexed for MEDLINE]
PMCID:: PMC1004648

Free PMC Article

Publication Types, MeSH Terms, Substances

Publication Types

Research Support, Non-U.S. Gov't

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Save items

Related citations in PubMed

Food intolerance in rheumatoid arthritis. I. A double blind, controlled trial of the clinical effects of elimination of milk allergens and azo dyes. [Ann Rheum Dis. 1992]
Food intolerance in rheumatoid arthritis. I. A double blind, controlled trial of the clinical effects of elimination of milk allergens and azo dyes.
van de Laar MA, van der Korst JK. Ann Rheum Dis. 1992 Mar; 51(3):298-302.
The gut-joint axis: cross reactive food antibodies in rheumatoid arthritis. [Gut. 2006]
The gut-joint axis: cross reactive food antibodies in rheumatoid arthritis.
Hvatum M, Kanerud L, Hällgren R, Brandtzaeg P. Gut. 2006 Sep; 55(9):1240-7. Epub 2006 Feb 16.
The elevated ratio of interferon gamma-/interleukin-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis patients can be changed by interleukin-4 but not by interleukin-10 or transforming growth factor beta. [Rheumatology (Oxford). 1999]
The elevated ratio of interferon gamma-/interleukin-4-positive T cells found in synovial fluid and synovial membrane of rheumatoid arthritis patients can be changed by interleukin-4 but not by interleukin-10 or transforming growth factor beta.
Yin Z, Siegert S, Neure L, Grolms M, Liu L, Eggens U, Radbruch A, Braun J, Sieper J. Rheumatology (Oxford). 1999 Nov; 38(11):1058-67.
Review Rheumatoid arthritis, food, and allergy. [Semin Arthritis Rheum. 1991]
Review Rheumatoid arthritis, food, and allergy.
van de Laar MA, van der Korst JK. Semin Arthritis Rheum. 1991 Aug; 21(1):12-23.
Review Morphological and molecular pathology of the B cell response in synovitis of rheumatoid arthritis. [Virchows Arch. 2002]
Review Morphological and molecular pathology of the B cell response in synovitis of rheumatoid arthritis.
Magalhães R, Stiehl P, Morawietz L, Berek C, Krenn V. Virchows Arch. 2002 Nov; 441(5):415-27. Epub 2002 Nov 5.

See reviews... See all...

Cited by 3 PubMed Central articles

Mediterranean diet intervention in rheumatoid arthritis. [Ann Rheum Dis. 2003]
Mediterranean diet intervention in rheumatoid arthritis.
Kjeldsen-Kragh J. Ann Rheum Dis. 2003 Mar; 62(3):193-5.
Food intolerance in rheumatoid arthritis. [Ann Rheum Dis. 1993]
Food intolerance in rheumatoid arthritis.
Abuzakouk M, O'Farrelly C. Ann Rheum Dis. 1993 Jan; 52(1):88.
Food intolerance in rheumatoid arthritis. I. A double blind, controlled trial of the clinical effects of elimination of milk allergens and azo dyes. [Ann Rheum Dis. 1992]
Food intolerance in rheumatoid arthritis. I. A double blind, controlled trial of the clinical effects of elimination of milk allergens and azo dyes.
van de Laar MA, van der Korst JK. Ann Rheum Dis. 1992 Mar; 51(3):298-302.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Food intolerance in rheumatoid arthritis. II. Clinical and histological aspects.
Food intolerance in rheumatoid arthritis. II. Clinical and histological aspects.
Ann Rheum Dis. 1992 Mar ;51(3):303-6.

PubMed
Role of mitochondria in neuronal cell death induced by oxidative stress; neuropr...
Role of mitochondria in neuronal cell death induced by oxidative stress; neuroprotection by Coenzyme Q10.
Neurobiol Dis. 2005 Apr ;18(3):618-27.

PubMed
Protection against group A streptococcal infection by vaccination with self-adju...
Protection against group A streptococcal infection by vaccination with self-adjuvanting lipid core M protein peptides.
Vaccine. 2005 Mar 18 ;23(17-18):2298-303.

PubMed
Designing high-quality interactive multimedia learning modules.
Designing high-quality interactive multimedia learning modules.
Comput Med Imaging Graph. 2005 Mar-Apr ;29(2-3):223-33.

PubMed
Pulse oximetry reference values at high altitude.
Pulse oximetry reference values at high altitude.
Arch Dis Child. 1992 Mar ;67(3):299-301.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: