Abstract
The aqueous extract of Viscum album leaves showed a significant coronary vasodilator activity on the Langendorff's isolated and perfused heart model. The data obtained suggest that the aqueous extract of V. album contains some biologically active principles that may act as inducers of the nitric oxide/soluble guanylate cyclase pathway.
MeSH terms
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Animals
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Coronary Circulation / drug effects
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Coronary Circulation / physiology
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Coronary Vessels / drug effects*
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Coronary Vessels / physiology
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Guanylate Cyclase / metabolism
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Guinea Pigs
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Heart / drug effects
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Heart / physiology
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Male
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Nitric Oxide / metabolism
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Plant Leaves
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Vasodilator Agents / administration & dosage
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Vasodilator Agents / pharmacology*
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Vasodilator Agents / therapeutic use
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Viscum album*
Substances
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Plant Extracts
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Vasodilator Agents
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Nitric Oxide
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Guanylate Cyclase