Dermatol Online J. 2005 Mar 1;11(1):3.

The potential immunomodulatory effects of topical retinoids.

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Department of Dermatology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. dajones@partners.org

Abstract

New research has refined our understanding of the immunopathophysiology of acne. Various immune factors, including both innate and adaptive immune responses, have been implicated in the pathophysiology of inflammatory acne. Topical retinoids such as tretinoin, adapalene, and tazarotene, exhibit immunomodulatory effects that may help to explain their efficacy in the resolution of inflammatory lesions.

PMID:: 15748544; [PubMed - indexed for MEDLINE]

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Topical retinoids in inflammatory acne: a retrospective, investigator-blinded, vehicle-controlled, photographic assessment. [Clin Ther. 2005]
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