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Yonsei Med J. 2005 Feb 28;46(1):184-8.

Littoral cell angioma (LCA) associated with liver cirrhosis.

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  • 1Department of Internal Medicine, Gastroenterology Division, Inha University Hospital, Inha University, 7-206, 3-ga, Shinheung-dong, Jung-gu, Incheon 400-103, Korea.


A littoral cell angioma (LCA) is a rare benign vascular tumor of the spleen. A 60-year-old man, with multiple nodules in imaging study and liver cirrhosis graded as Child-Pugh classification class A, was transferred for splenomegaly. A thrombocytopenia was found on hematological evaluation. Because there was no evidence of hematological and visceral malignancy, a splenectomy was performed for a definitive diagnosis. The histological and immunohistochemical features of the splenic specimens were consistent with a LCA. After the splenectomy, the thrombocytopenia recovered to the normal platelet count. There has been no previous report of a LCA combined with liver cirrhosis. Herein, the first case of a LCA in Korea, diagnosed and treated by a splenectomy, is reported.

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