Send to

Choose Destination
See comment in PubMed Commons below
J Bacteriol. 2005 Mar;187(6):2215-7.

Kinetic characterization of the glycosyltransferase module of Staphylococcus aureus PBP2.

Author information

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA.


We report the heterologous overexpression and purification of Staphylococcus aureus PBP2 and demonstrate efficient glycan polymerization from lipid II in vitro. S. aureus PBP2 is the first purified gram-positive class A penicillin-binding protein to show good transglycosylase activity. This enables further studies on this important class of enzymes.

[PubMed - indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk