Coron Artery Dis. 2005 Mar;16(2):93-7.

Mesenchymal stem cells in the infarcted heart.

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Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02118, USA.

Abstract

A loss of functional cardiomyocytes forms the cellular basis of cardiac dysfunction and heart failure. Stem cell based repletion of scarred myocardial tissue and regeneration of cardiomyocytes have been proposed as a potential treatment of ventricular dysfunction. In this review, we provide an overview of recent studies utilizing mesenchymal stem cells in cardiac regeneration and post-myocardial infarct therapy.

PMID:: 15735401; [PubMed - indexed for MEDLINE]

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Cited by 3 PubMed Central articles

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