Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Am Soc Mass Spectrom. 2005 Mar;16(3):312-23.

Investigation of electrospray ionization and electrostatic focusing devices using a three-dimensional electrospray current density profiler.

Author information

  • 1Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, USA. jj@unc.edu

Abstract

A novel instrument for profiling the current density of nanoelectrospray ionization plumes in three dimensions has been developed. A hemispherically-shaped electrostatic lens at atmospheric pressure is found to be able to compress the space-charge in nano-ESI and increase the average current density in the plume to three times the nominal value. Ion transmission into a single-quadrupole mass spectrometer is found to roughly double using the electrostatic lens. Data also suggest that ion transmission into the first vacuum region for a skimmer-type mass spectrometer interface using nano-ESI may be typically 40% or better with no special focusing device used.

PMID:
15734324
[PubMed]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Springer Icon for Elsevier Science
    Loading ...
    Write to the Help Desk