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Childs Nerv Syst. 2006 Jan;22(1):28-32. Epub 2005 Feb 10.

Latex sensitisation and allergy in children with myelomeningocele.

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  • 1Paediatric Department, Spina Bifida Centre, Policlinico A. Gemelli, Largo A. Gemelli 8, 00168 Rome, Italy. c.rendeli@libero.it

Abstract

INTRODUCTION:

Children with spina bifida (SB) have a high degree of exposure to latex products as a consequence of repeated surgical procedures, implantation of latex-containing materials and catheterisation. The consequence is a higher incidence of latex allergic reactions.

OBJECTIVE:

The aim of this study is to evaluate the prevalence of latex sensitisation and allergy in a population of children with myelomeningocele (MMC) and to assess the role of associated risk factors.

RESULTS:

Forty-eight percent of the patients (29 out of 60) showed a latex sensitisation with specific IgE >0.7 kU/l while 15% (9 out of 60) were allergic to latex (specific IgE >0.7 kU/l and clinical manifestations). The principal factor correlated with allergy to latex was specific serum IgE to latex (radioallergosorbent test [RAST]) values (p<0.01). Other factors were total serum IgE (paper radioimmunosorbent test [PRIST]) values, number of surgical procedures and familiarity with allergy.

CONCLUSION:

These results underline the importance of prophylactic measures to avoid the exposure, not only in the sanitary environment, through the institution of latex-safe routes, but also in daily life, to prevent potentially serious allergic reactions.

[PubMed - indexed for MEDLINE]
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