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Radiol Clin North Am. 2005 Jan;43(1):221-34, xii.

Non-PET functional imaging techniques: optical.

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  • 1Biomedical Optical Imaging, Advanced Research Technologies (ART), 2300 Alfred-Nobel Boulevard, Saint-Laurent, Quebec H4S 2A4, Canada. xintes@art.ca


The strong and steady development of diffuse optical spectroscopy and tomography as new biomedical optics technologies promises to bring these optical techniques into clinical practice. This article provides a brief review of the light-tissue interaction, the instrumentation, and the theory relevant to this field. This is followed by a survey of the three main applications: brain imaging, muscle imaging, and breast imaging. Lastly, the future outlook of the technology is presented, highlighting the new promises based on recent breakthroughs.

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