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Stroke. 2005 Mar;36(3):e20-2. Epub 2005 Feb 3.

Localized reversible reduction of apparent diffusion coefficient in transient hypoglycemia-induced hemiparesis.

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  • 1Department of Diagnostic and Interventional Radiology, Friedrich-Schiller-University Jena, Erlanger Allee 101, 07747 Jena, Germany. joachim.boettcher@med.uni-jena.de

Abstract

BACKGROUND AND PURPOSE:

The pathophysiology of hypoglycemia shares a common mechanism with cerebral ischemia, but so far, little is known regarding MRI of humans with hypoglycemia.

METHODS:

We report a patient with left hemiparesis and dysarthria associated with a blood glucose level of 1.7 mmol/L. The patient recovered completely after glucose infusion.

RESULTS:

The initial diffusion-weighted imaging (DWI) showed increased signal intensities and a reduction of apparent diffusion coefficient (ADC) values localized in the corpus callosum (splenium) and asymmetrically in the corona radiata. After 48 hours, follow-up revealed complete recovery of DWI and ADC signal abnormalities.

CONCLUSIONS:

To our knowledge, this is the first presentation of a case with transient hypoglycemia-induced focal neurological deficits revealing completely reversible MRI changes in terms of disturbed DWI and ADC with a peculiar as yet undescribed topography.

PMID:
15692119
[PubMed - indexed for MEDLINE]
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