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Brain. 2005 Mar;128(Pt 3):454-71. Epub 2005 Feb 2.

Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: a European consensus statement.

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  • 1Department of Epileptology, University of Bonn, Sigmund-Freud-Str. 25, 53105 Bonn, Germany.


Rasmussen encephalitis (RE) is a rare but severe immune-mediated brain disorder leading to unilateral hemispheric atrophy, associated progressive neurological dysfunction and intractable seizures. Recent data on the pathogenesis of the disease, its clinical and paraclinical presentation, and therapeutic approaches are summarized. Based on these data, we propose formal diagnostic criteria and a therapeutic pathway for the management of RE patients.

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