Abstract
Syntheses of the enantiomerically pure phytoprostanes B(1) type I and II are described starting from furfural and n-propylfuran. Key steps include the preparation of the Freimanis (+/-)-hydroxycyclopentenone and Wittig coupling using chiral phosphonium salts.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alkenes / chemical synthesis*
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Fatty Acids, Unsaturated
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Furaldehyde / chemistry
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Furaldehyde / metabolism
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Furans / chemical synthesis*
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Furans / chemistry*
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Furans / metabolism
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Stereoisomerism
Substances
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Alkenes
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Fatty Acids, Unsaturated
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Furans
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phytoprostane B1 type I
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phytoprostane B1 type II
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Furaldehyde