Curr Opin Investig Drugs. 2005 Jan;6(1):58-64.

EEG and laser stimulation as tools for pain research.

Source

Unité de Réadaptation et Médecine Physique (READ), Université Catholique de Louvain, B-1200 Brussels, Belgium. plaghki@read.ucl.ac.be

Abstract

Laser heat stimulators selectively activate Adelta and C-nociceptors in the superficial layers of the skin. Their high power output produces steep heating ramps, which improve synchronization of afferent volleys and therefore allow the recording of time-locked events, such as laser-evoked brain potentials. Study of the electrical brain activity evoked by Adelta- and C-nociceptor afferent volleys revealed the existence of an extensive, sequentially activated, cortical network. These electrophysiological responses are modulated by stimulus-driven and, even more extensively, top-down processes. The specificity and validity of these components for pain research are currently under intense scrutiny.

PMID:: 15675604; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

Review

MeSH Terms

LinkOut - more resources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Pain - MedlinePlus Health Information

Supplemental Content

Related citations

Operculoinsular cortex encodes pain intensity at the earliest stages of cortical processing as indicated by amplitude of laser-evoked potentials in humans. [Neuroscience. 2005]
Operculoinsular cortex encodes pain intensity at the earliest stages of cortical processing as indicated by amplitude of laser-evoked potentials in humans.
Iannetti GD, Zambreanu L, Cruccu G, Tracey I. Neuroscience. 2005; 131(1):199-208.
Adelta nociceptor response to laser stimuli: selective effect of stimulus duration on skin temperature, brain potentials and pain perception. [Clin Neurophysiol. 2004]
Adelta nociceptor response to laser stimuli: selective effect of stimulus duration on skin temperature, brain potentials and pain perception.
Iannetti GD, Leandri M, Truini A, Zambreanu L, Cruccu G, Tracey I. Clin Neurophysiol. 2004 Nov; 115(11):2629-37.
Single-trial detection of human brain responses evoked by laser activation of Adelta-nociceptors using the wavelet transform of EEG epochs. [Neurosci Lett. 2004]
Single-trial detection of human brain responses evoked by laser activation of Adelta-nociceptors using the wavelet transform of EEG epochs.
Mouraux A, Plaghki L. Neurosci Lett. 2004 May 6; 361(1-3):241-4.
Review Laser-evoked cerebral potentials in the assessment of cutaneous pain sensitivity in normal subjects and patients. [Rev Neurol (Paris). 1991]
Review Laser-evoked cerebral potentials in the assessment of cutaneous pain sensitivity in normal subjects and patients.
Bromm B, Treede RD. Rev Neurol (Paris). 1991; 147(10):625-43.
Review Human brain processing and central mechanisms of pain as observed by electro- and magneto-encephalography. [J Chin Med Assoc. 2004]
Review Human brain processing and central mechanisms of pain as observed by electro- and magneto-encephalography.
Kakigi R, Inui K, Tran DT, Qiu Y, Wang X, Watanabe S, Hoshiyama M. J Chin Med Assoc. 2004 Aug; 67(8):377-86.

See reviews... See all...

Cited by 2 PubMed Central articles

Selective nociceptor activation in volunteers by infrared diode laser. [Mol Pain. 2011]
Selective nociceptor activation in volunteers by infrared diode laser.
Tzabazis AZ, Klukinov M, Crottaz-Herbette S, Nemenov MI, Angst MS, Yeomans DC. Mol Pain. 2011 Mar 22; 7:18. Epub 2011 Mar 22.
Quantitative pinch stimulator for exploring evoked nociceptive responses: a pilot study. [Biomed Eng Online. 2010]
Quantitative pinch stimulator for exploring evoked nociceptive responses: a pilot study.
Chen CP, Liao WL, Tseng YL, Lu PL, Lo YC, Chen YY, Jaw FS. Biomed Eng Online. 2010 Nov 24; 9:79. Epub 2010 Nov 24.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

EEG and laser stimulation as tools for pain research.
EEG and laser stimulation as tools for pain research.
Curr Opin Investig Drugs. 2005 Jan ;6(1):58-64.

PubMed
Lost in localization: the need for a universal coordinate database.
Lost in localization: the need for a universal coordinate database.
Neuroimage. 2009 Oct 15 ;48(1):1-7. Epub 2009 Feb 5 .

PubMed
Quantitative Meta-Analysis on State and Trait Aspects of Auditory Verbal Halluci...
Quantitative Meta-Analysis on State and Trait Aspects of Auditory Verbal Hallucinations in Schizophrenia.
Schizophr Bull. 2010 Dec 22. [Epub ahead of print]

PubMed
Deep brain stimulation for obsessive-compulsive disorder: past, present, and fut...
Deep brain stimulation for obsessive-compulsive disorder: past, present, and future.
Neurosurg Focus. 2010 Aug ;29(2):E10.

PubMed
Perceived ugliness: an update on treatment-relevant aspects of body dysmorphic d...
Perceived ugliness: an update on treatment-relevant aspects of body dysmorphic disorder.
Curr Psychiatry Rep. 2011 Aug ;13(4):283-8.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: