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J Obstet Gynecol Neonatal Nurs. 2005 Jan-Feb;34(1):87-92.

The association between acute fatty liver of pregnancy and fatty acid oxidation disorders.

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  • 1St. Louis Children's Hospital, 1 Children's Place, St. Louis, MO 63110, USA.


Acute fatty liver of pregnancy is a relatively rare but potentially fatal liver disorder of late pregnancy. Recent advances in molecular diagnostic procedures provide evidence of a genetic basis for this condition and a link to offspring disorders in fatty acid oxidation. This relationship implies the need for genetic testing and follow-up of at-risk women and their neonates.

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