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Trends Neurosci. 2005 Feb;28(2):59-62.

Quantal transmission: not just for neurons.

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  • 1Vollum Institute, L474, Oregon Health & Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.


Glia have moved into the spotlight as participants in synaptic signaling. Recent work by Bergles and colleagues extends this active role by showing that oligodendrocyte precursors cells (OPCs) in the hippocampus receive functional glutamatergic and GABAergic synapses. Synaptic signaling in these cells could provide a mechanism for activity-dependent modulation of OPC proliferation and differentiation.

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