Tumori. 2004 Sep-Oct;90(5):498-500.

Invasive ductal carcinoma of the breast with a large central acellular zone associated with matrix-producing carcinoma.

Hama Y, Tsuda H, Sato K, Hiraide H, Mochizuki H, Kusano S.

Source

Department of Radiology, National Defense Medical College, Namiki, Tokorozawa, Saitama, Japan. yjhama@me.ndmc.ac.jp

Abstract

Matrix-producing carcinoma is a variant of metaplastic carcinoma of the breast that consists of overt carcinoma with direct transition to a cartilagenous and osseous stromal matrix. A clinicopathological association between MPC and high-grade invasive ductal carcinoma with a large central acellular zone has been recently discussed. However, few reports have ever shown the radiological, pathological and immunohistochemical correlation of this unique tumor. We present a case of 27-year-old woman with matrix-producing carcinoma with a large central acellular zone, which was characterized by a large homogeneous hypodense center with well-marginated, ring-like enhancement on contrast enhanced computerized tomography.

PMID:: 15656336; [PubMed - indexed for MEDLINE]

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