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    Neurology. 1992 Apr;42(4):891-6.

    Improvement of motor performance of HIV-positive patients under AZT therapy.

    Arendt G, Hefter H, Buescher L, Hilperath F, Elsing C, Freund HJ.

    Source

    Department of Neurology, University of Duesseldorf, Germany.

    Abstract

    We performed motor tests (most rapid alternating movements [MRAMs] of index fingers and most rapid contractions [MRCs] of voluntary isometric index finger extensions) in HIV-positive patients with (group 1) and without (group 2) AZT treatment over a 6-month period. Whereas MRAMs remained uninfluenced, MRCs showed a clear improvement in the treated group and a decline in the nontreated group, according to the T helper cell counts. MRCs were not only a sensitive test procedure for detecting subclinical lesions in HIV-positive patients, but also a reliable therapy control measurement.

    PMID:
    1565249
    [PubMed - indexed for MEDLINE]

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