Your browser version may not work well with NCBI's Web applications. More information here...
1: J Org Chem. 2005 Jan 21;70(2):433-8.Click here to read Links

Polystyrene-supported (R)-2-piperazino-1,1,2-triphenylethanol: a readily available supported ligand with unparalleled catalytic activity and enantioselectivity.

Castellnou D, Solà L, Jimeno C, Fraile JM, Mayoral JA, Riera A, Pericàs MA.

Institute of Chemical Research of Catalonia (ICIQ), 43007 Tarragona, Spain.

A very active and highly enantioselective catalytic resin, designed for minimal perturbation of the catalytic center by the polymer matrix, has been assembled in two steps from (S)-triphenylethylene oxide, piperazine, and Merrifield resin and tested in the enantioselective ethylation of aldehydes. 1-Arylpropanols of 94-95% ee are obtained in high yield by the use of only 2 mol % of catalytic resin at 0 degrees C for 4 h.

PMID: 15651783 [PubMed]