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Bioinformatics. 2005 May 1;21(9):2104-5. Epub 2005 Jan 12.

ProtTest: selection of best-fit models of protein evolution.

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  • 1Department of Biochemistry, Genetics and Immunology, Universidad de Vigo, Spain.



Using an appropriate model of amino acid replacement is very important for the study of protein evolution and phylogenetic inference. We have built a tool for the selection of the best-fit model of evolution, among a set of candidate models, for a given protein sequence alignment.


ProtTest is available under the GNU license from

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