Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2004 Dec;12(6):875-9.

[The immuno-deficient mice transplantion models in study of human hematopoietic stem cells--review].

[Article in Chinese]

Source

Hubei Stem Cell Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Abstract

A variety of immuno-deficient animal models has been used in the detection of human hematopoietic stem/progenitor cells and up to date make many remarkable contribution to the study of detectron cell biology. An ideal immuno-deficient animal should not only have complete immune defects, be able to transplant human hematopoietic stem/progenitor cells with high efficacy, but also survive long enough for observation. In this review, the development of immuno-deficient mice from nude, SCID, to NOD/SCID etc is introduced and much attention is put on the features, priority and shortcomings of those key animal models and their application in HSC research. The progress, the future directions and prospects of these immuno-deficient mice models are stressed.

PMID:: 15631683; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Medical

Stem Cells - MedlinePlus Health Information

Supplemental Content

Save items

Related citations in PubMed

Review Immune-deficient mouse models for analysis of human stem cells. [Biotechniques. 2003]
Review Immune-deficient mouse models for analysis of human stem cells.
Meyerrose TE, Herrbrich P, Hess DA, Nolta JA. Biotechniques. 2003 Dec; 35(6):1262-72.
Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells. [Blood. 2005]
Human short-term repopulating stem cells are efficiently detected following intrafemoral transplantation into NOD/SCID recipients depleted of CD122+ cells.
McKenzie JL, Gan OI, Doedens M, Dick JE. Blood. 2005 Aug 15; 106(4):1259-61. Epub 2005 May 5.
NOD/SCID repopulating cells contribute only to short-term repopulation in the baboon. [Gene Ther. 2008]
NOD/SCID repopulating cells contribute only to short-term repopulation in the baboon.
Mezquita P, Beard BC, Kiem HP. Gene Ther. 2008 Nov; 15(21):1460-2. Epub 2008 Jun 19.
CD26 inhibition on CD34+ or lineage- human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-term engraftment into NOD/SCID/Beta2null immunodeficient mice. [Stem Cells Dev. 2007]
CD26 inhibition on CD34+ or lineage- human umbilical cord blood donor hematopoietic stem cells/hematopoietic progenitor cells improves long-term engraftment into NOD/SCID/Beta2null immunodeficient mice.
Christopherson KW 2nd, Paganessi LA, Napier S, Porecha NK. Stem Cells Dev. 2007 Jun; 16(3):355-60.
Review The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in NOD-SCID/IL2rgamma(null) mice. [Curr Top Microbiol Immunol. 2008]
Review The differentiative and regenerative properties of human hematopoietic stem/progenitor cells in NOD-SCID/IL2rgamma(null) mice.
Ishikawa F, Saito Y, Yoshida S, Harada M, Shultz LD. Curr Top Microbiol Immunol. 2008; 324:87-94.

See reviews... See all...

Recent activity

Clear Turn Off Turn On

[The immuno-deficient mice transplantion models in study of human hematopoietic ...
[The immuno-deficient mice transplantion models in study of human hematopoietic stem cells--review].
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2004 Dec ;12(6):875-9.

PubMed
Surgical treatment of giant-cell tumors of the spine.
Surgical treatment of giant-cell tumors of the spine.
Clin Orthop Relat Res. 1992 May ;(278):29-36.

PubMed
Core biopsy as a tool in planning the management of invasive breast cancer.
Core biopsy as a tool in planning the management of invasive breast cancer.
World J Surg Oncol. 2005 Jan 4;3(1):1.

PubMed
Development of a psychometrically sound internet addiction scale: a preliminary ...
Development of a psychometrically sound internet addiction scale: a preliminary step.
Psychol Addict Behav. 2004 Dec ;18(4):381-4.

PubMed
In vitro and in vivo evaluation of antibiotic diffusion from antibiotic-impregna...
In vitro and in vivo evaluation of antibiotic diffusion from antibiotic-impregnated polymethylmethacrylate beads.
Clin Orthop Relat Res. 1992 May ;(278):244-52.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

[The immuno-deficient mice transplantion models in study of human hematopoietic stem cells--review].

Source

Abstract

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Medical

Supplemental Content

Save items

Related citations in PubMed

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information