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J Rheumatol. 2005 Jan;32(1):181-3.

Successful treatment of long-standing neuro-Behçet's disease with infliximab.

Author information

  • 1Section of Rheumatology, Department of Medicine, Louisiana State University Health Sciences Center, New Orleans, Louisiana 70112, USA.

Abstract

Behçet's disease is a chronic relapsing form of vasculitis affecting multiple organs. Central nervous system involvement is a common presentation. Tumor necrosis factor-alpha (TNF-alpha) is considered to play a major role in the disease pathogenesis. We describe a patient with a long history of neuro-Behçet's disease who showed a remarkable response to infliximab therapy. Given the variable and limited success of other interventions, the use of anti-TNF-alpha therapy seems to be effective for patients with refractory disease.

PMID:
15630746
[PubMed - indexed for MEDLINE]
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