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Cell. 2004 Dec 29;119(7):901-2.

Ribosome biogenesis: giant steps for a giant problem.

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  • 1Section of Molecular and Cellular Biology and Center for Genetics and Development, Division of Biological Sciences, University of California, Davis, CA 95616, USA.

Abstract

In this issue of Cell, the Hall group describes how the rapamycin-sensitive TOR signaling network controls ribosomal protein (RP) gene expression via the Forkhead-like transcription factor FHL1 in budding yeast (Martin et al., 2004). These findings represent a crucial advance in our understanding of the mechanism by which TOR regulates ribosome biogenesis in response to environmental cues.

PMID:
15620347
[PubMed - indexed for MEDLINE]
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