[Salt and hypertension--100 years of unresolved issues]

Tidsskr Nor Laegeforen. 2004 Dec 16;124(24):3191-3.
[Article in Norwegian]

Abstract

Background: In recent years, criticism against the so-called "salt hypothesis" has gained momentum. We give a brief review of important data related to this issue, in particular of the evidence-based documentation supporting a general recommendation of reduced salt intake.

Material and methods: We searched in PubMed, Ovid and HighWire for papers relating to salt intake, blood pressure and cardiovascular disease.

Results: Most studies in favour of the salt hypothesis rely on short-term (about 30 days) intervention trials. The possible benefit of salt restriction on hypertension and hypertension-related morbidity and mortality is not firmly established.

Interpretation: A general recommendation of a reduction in salt intake among Norwegians to 5 g/day or less is not scientifically justified. More studies on salt intake in the general Norwegian population as well as intervention trials spanning years are warranted.

Publication types

  • English Abstract
  • Historical Article
  • Review

MeSH terms

  • Animals
  • Cardiovascular Diseases / etiology
  • Cardiovascular Diseases / history
  • Cardiovascular Diseases / prevention & control
  • Diet, Sodium-Restricted
  • History, 20th Century
  • Humans
  • Hypertension / diet therapy
  • Hypertension / etiology*
  • Hypertension / history
  • Sodium Chloride, Dietary / administration & dosage
  • Sodium Chloride, Dietary / adverse effects*
  • Sodium Chloride, Dietary / history

Substances

  • Sodium Chloride, Dietary