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Nucleic Acids Res. 2005 Jan 1;33(Database issue):D279-83.

PFD: a database for the investigation of protein folding kinetics and stability.

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  • 1The Department of Biochemistry and Molecular Biology, School of Biomedical Sciences, Faculty of Medicine, PO Box 53, Monash University, Clayton, Victoria 3800, Australia.


We have developed a new database that collects all protein folding data into a single, easily accessible public resource. The Protein Folding Database (PFD) contains annotated structural, methodological, kinetic and thermodynamic data for more than 50 proteins, from 39 families. A user-friendly web interface has been developed that allows powerful searching, browsing and information retrieval, whilst providing links to other protein databases. The database structure allows visualization of folding data in a useful and novel way, with a long-term aim of facilitating data mining and bioinformatics approaches. PFD can be accessed freely at

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