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Bioinformatics. 2005 Apr 15;21(8):1703-4. Epub 2004 Dec 14.

CARHTA GENE: multipopulation integrated genetic and radiation hybrid mapping.

Author information

  • 1INRA, Biométrie et Intelligence Artificielle/Génétique Cellulaire, BP 27, 31326 Castanet-Tolosan Cedex, France.

Abstract

CAR(H)(T)A GENE: is an integrated genetic and radiation hybrid (RH) mapping tool which can deal with multiple populations, including mixtures of genetic and RH data. CAR(H)(T)A GENE: performs multipoint maximum likelihood estimations with accelerated expectation-maximization algorithms for some pedigrees and has sophisticated algorithms for marker ordering. Dedicated heuristics for framework mapping are also included. CAR(H)(T)A GENE: can be used as a C++ library, through a shell command and a graphical interface. The XML output for companion tools is integrated.

AVAILABILITY:

The program is available free of charge from www.inra.fr/bia/T/CarthaGene for Linux, Windows and Solaris machines (with Open Source).

CONTACT:

tschiex@toulouse.inra.fr.

PMID:
15598829
[PubMed - indexed for MEDLINE]
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