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J Inorg Biochem. 2005 Jan;99(1):324-36.

Cytochrome c oxidase, ligands and electrons.

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  • 1Department of Biochemical Sciences A. Rossi Fanelli and CNR Institute of Molecular Biology and Pathology, University of Rome La Sapienza, P. le Aldo Moro, 5, I-00185 Roma, Italia. maurizio.brunori@uniroma1.it


We present hereby an overview of the reactions of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, with ligands (primarily oxygen) and electrons, pointing out where necessary unresolved facts or questionable interpretations.

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