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ME Müller-Institute for High-Resolution Electron Microscopy at the Biocenter, University of Basel, Basel, Switzerland.
A consensus view on the three-dimensional structure of the F-actin filament and the relative strength of the intersubunit contacts in the filament has been established from an atomic filament model and recent three-dimensional reconstructions from electron micrographs of F-actin filaments. Functional implications of recent structural and biochemical data indicating a rather dynamic filament structure are discussed.
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