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1: Bioorg Med Chem Lett. 2005 Jan 3;15(1):81-4.Click here to read Links

Optimization of pyrrolidinone based HIV protease inhibitors.

Sherrill RG, Andrews CW, Bock WJ, Davis-Ward RG, Furfine ES, Hazen RJ, Rutkowske RD, Spaltenstein A, Wright LL.

GlaxoSmithKline, 5 Moore Drive, Research Triangle Park, NC 27709, USA. ron.g.sherrill@gsk.com

Optimization of P1-substituted pyrrolidinone based HIV protease inhibitors has yielded analogs with very potent antiviral activity.

PMID: 15582415 [PubMed - indexed for MEDLINE]