Rev Cardiovasc Med. 2004 Fall;5(4):189-93.

The relationship of cigarette smoking to peripheral arterial disease.

Source

Cardiovascular Division, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

Abstract

Cigarette smoking is one of the most important risk factors for peripheral arterial disease (PAD). Smoking increases the risk of PAD by several fold and is a more influential risk factor for PAD than for coronary artery disease. Multiple pathophysiologic mechanisms may account for the prevalence of atherosclerosis in cigarette smokers. These include abnormalities of endothelial function, lipoprotein metabolism, coagulation, and platelet function. Smoking cessation decreases the risk of cardiovascular morbidity and mortality, and may improve functional capacity in patients with PAD. Therapies to promote smoking cessation include counseling, nicotine replacement, and bupropion. Healthcare providers must enhance their efforts and target smoking cessation as a modifiable risk factor in patients with PAD and other manifestations of atherosclerosis.

PMID:: 15580157; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Grant Support

Publication Types

MeSH Terms

Grant Support

LinkOut - more resources

Medical

Smoking - MedlinePlus Health Information

Supplemental Content

Related citations

The relationship between cigarette smoking and cardiovascular risk factors in peripheral arterial disease compared with ischaemic heart disease. The Edinburgh Artery Study. [Eur Heart J. 1995]
The relationship between cigarette smoking and cardiovascular risk factors in peripheral arterial disease compared with ischaemic heart disease. The Edinburgh Artery Study.
Leng GC, Lee AJ, Fowkes FG, Lowe GD, Housley E. Eur Heart J. 1995 Nov; 16(11):1542-8.
Relationship between smoking and cardiovascular risk factors in the development of peripheral arterial disease and coronary artery disease: Edinburgh Artery Study. [Eur Heart J. 1999]
Relationship between smoking and cardiovascular risk factors in the development of peripheral arterial disease and coronary artery disease: Edinburgh Artery Study.
Price JF, Mowbray PI, Lee AJ, Rumley A, Lowe GD, Fowkes FG. Eur Heart J. 1999 Mar; 20(5):344-53.
Risk factors for peripheral arterial disease incidence in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study. [Atherosclerosis. 2005]
Risk factors for peripheral arterial disease incidence in persons with diabetes: the Atherosclerosis Risk in Communities (ARIC) Study.
Wattanakit K, Folsom AR, Selvin E, Weatherley BD, Pankow JS, Brancati FL, Hirsch AT. Atherosclerosis. 2005 Jun; 180(2):389-97. Epub 2005 Jan 25.
Review Cardiovascular morbidity and mortality in peripheral arterial disease. [Curr Drug Targets Cardiovasc H...]
Review Cardiovascular morbidity and mortality in peripheral arterial disease.
Eberhardt RT, Coffman JD. Curr Drug Targets Cardiovasc Haematol Disord. 2004 Sep; 4(3):209-17.
Review Smoking and cardiovascular disease. [Am J Med. 1992]
Review Smoking and cardiovascular disease.
Lakier JB. Am J Med. 1992 Jul 15; 93(1A):8S-12S.

See reviews... See all...

Cited by 6 PubMed Central articles

Suboptimal use of risk reduction therapy in peripheral arterial disease patients at a major teaching hospital. [Ann Saudi Med. 2011]
Suboptimal use of risk reduction therapy in peripheral arterial disease patients at a major teaching hospital.
Al-Omran M, Verma S, Lindsay TF. Ann Saudi Med. 2011 Jul-Aug; 31(4):371-5.
Cumulative smoking exposure, duration of smoking cessation, and peripheral arterial disease in middle-aged and older Korean men. [BMC Public Health. 2011]
Cumulative smoking exposure, duration of smoking cessation, and peripheral arterial disease in middle-aged and older Korean men.
Lee YH, Shin MH, Kweon SS, Choi JS, Rhee JA, Ahn HR, Yun WJ, Ryu SY, Kim BH, Nam HS, et al. BMC Public Health. 2011 Feb 11; 11:94. Epub 2011 Feb 11.
Effects of the vasodilating beta-blocker nebivolol on smoking-induced endothelial dysfunction in young healthy volunteers. [Vasc Health Risk Manag. 2008]
Effects of the vasodilating beta-blocker nebivolol on smoking-induced endothelial dysfunction in young healthy volunteers.
Schmidt AC, Flick B, Jahn E, Bramlage P. Vasc Health Risk Manag. 2008; 4(4):909-15.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.
Cited in Books
NCBI Bookshelf books that cite the current articles.

Recent activity

Clear Turn Off Turn On

The relationship of cigarette smoking to peripheral arterial disease.
The relationship of cigarette smoking to peripheral arterial disease.
Rev Cardiovasc Med. 2004 Fall ;5(4):189-93.

PubMed
Cigarette smoking and hypertension.
Cigarette smoking and hypertension.
Curr Pharm Des. 2010 ;16(23):2518-25.

PubMed
Slow walking speed in elderly people.
Slow walking speed in elderly people.
BMJ. 2009 Nov 10 ;339:b4236. doi: 10.1136/bmj.b4236.

PubMed
Autism treatment survey: services received by children with autism spectrum diso...
Autism treatment survey: services received by children with autism spectrum disorders in public school classrooms.
J Autism Dev Disord. 2008 May ;38(5):961-71.

PubMed
Parents' views and experiences about complementary and alternative medicine trea...
Parents' views and experiences about complementary and alternative medicine treatments for their children with autistic spectrum disorder.
J Autism Dev Disord. 2010 Apr ;40(4):494-503.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Display Settings:

Send to: