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Med Oral Patol Oral Cir Bucal. 2004 Nov-Dec;9(5):381-4; 377-80.

Oral cancer risk and molecular markers.

[Article in English, Spanish]

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  • 1Facultad de Odontología, Universidad de Barcelona. 13598eck@comb.es

Abstract

The clinical appearance and, especially, the degree of dysplasia that may be shown by pre-cancerous lesions in the oral cavity suggest a potential for malignisation. An increasing number of studies are seeking new, more specific markers that would help to determine the degree of cell alteration and enable a better understanding of the degree of malignant degeneration of these cells. The present review considers the most recent findings for these markers, grouping them into families: tumour growth markers; markers of tumour suppression and anti-tumour response; angiogenesis markers; markers of tumour invasion and metastatic potential; cell surface markers; intracellular markers; markers derived from arachidonic acid; and enzymatic markers.

PMID:
15580114
[PubMed - indexed for MEDLINE]
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