Abstract
Hen egg is a nutritional store for a new life. We examined the effect of egg yolk proteins on longitudinal bone growth in the rat. Protein fractions from egg yolk were tested. Milk protein, casein, was used as a control. The bone growth rate was significantly increased by yolk water-soluble protein (YSP, 100 mg/kg) administration for 5 d. The bone morphogenetic protein-2 immunostaining of growth plate was also increased. Considering the results, YSP can be used as a growth-promoting factor.
MeSH terms
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Animals
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Benzoxazines
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Bone Development / drug effects*
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Bone Morphogenetic Protein 2
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Bone Morphogenetic Proteins / metabolism
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Bone and Bones / cytology
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Caseins / pharmacology
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Chondrocytes / drug effects
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Egg Proteins / pharmacology*
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Male
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Oxazines
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Rats
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Rats, Sprague-Dawley
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Stimulation, Chemical
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Transforming Growth Factor beta / metabolism
Substances
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Benzoxazines
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Bmp2 protein, rat
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Bone Morphogenetic Protein 2
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Bone Morphogenetic Proteins
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Caseins
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Egg Proteins
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Oxazines
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Transforming Growth Factor beta
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cresyl violet