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1: Medicina (B Aires). 2004;64(5):442-4.Links

[Severe cardiac disease in scleroderma]

[Article in Spanish]

Grinberg AR, Sabate D, Sarano JF, Alvarez CL.

Servicio de Clínica Médica, Instituto de Investigaciones Médicas Alfredo Lanari, Facultad de Medicina, Universidad de Buenos Aires, Argentina. alejandrogrinberg@yahoo.com

A 36 year-old female with a diagnosis of systemic sclerosis suffered from an acute episode of skeletal myositis and refractory heart failure with cardiogenic shock. Despite immunosuppressive treatment with high doses of corticosteroids and hemodynamic support she died five days after admission. The autopsy showed cardiac myocytolysis, myocyte necrosis and contraction band necrosis. There are very few reported cases of severe heart failure associated to systemic sclerosis.

PMID: 15560548 [PubMed - indexed for MEDLINE]