Clin Infect Dis. 1992 Feb;14(2):472-8.

Invasive infections due to Candida krusei: report of ten cases of fungemia that include three cases of endophthalmitis.

McQuillen DP, Zingman BS, Meunier F, Levitz SM.

Source

Section of Infectious Diseases, Boston Department of Veterans Affairs Medical Center, Massachusetts.

Abstract

Candida krusei has become an increasingly important invasive pathogen, particularly in immunocompromised patients. Previous experimental and clinical experience suggest that C. krusei has a low propensity for hematogenously infecting the eye. We report 10 cases of fungemia due to C. krusei at our institutions, including three cases of endophthalmitis due to C. krusei. Fungemia was associated with nodular skin lesions in all seven patients with neutropenia and occurred despite administration of antifungal prophylaxis or empirical therapy. None of the patients apparently died as a direct result of C. krusei fungemia. Treatment with amphotericin B resulted in resolution of endophthalmitis, although one patient required vitrectomy. Early institution of aggressive therapy with amphotericin B may alter the course and improve the prognosis of C. krusei infection, particularly in immunocompromised patients.

PMID:: 1554833; [PubMed - indexed for MEDLINE]

Publication Types, MeSH Terms, Substances

Publication Types

Case Reports

MeSH Terms

Substances

Amphotericin B

LinkOut - more resources

Full Text Sources

Medical

Molecular Biology Databases

AMPHOTERICIN B - HSDB

Supplemental Content

Save items

Related citations in PubMed

Review Hematogenous endophthalmitis due to Candida tropicalis: report of two cases and review. [Clin Infect Dis. 1993]
Review Hematogenous endophthalmitis due to Candida tropicalis: report of two cases and review.
Cohen M, Montgomerie JZ. Clin Infect Dis. 1993 Aug; 17(2):270-2.
Candida krusei fungemia. An escalating serious infection in immunocompromised patients. [Arch Intern Med. 2000]
Candida krusei fungemia. An escalating serious infection in immunocompromised patients.
Abbas J, Bodey GP, Hanna HA, Mardani M, Girgawy E, Abi-Said D, Whimbey E, Hachem R, Raad I. Arch Intern Med. 2000 Sep 25; 160(17):2659-64.
Review Candida krusei fungemia. Report of 4 cases and review of the literature. [Medicine (Baltimore). 1993]
Review Candida krusei fungemia. Report of 4 cases and review of the literature.
Goldman M, Pottage JC Jr, Weaver DC. Medicine (Baltimore). 1993 May; 72(3):143-50.
Candida glabrata and Candida krusei fungemia after high-risk allogeneic marrow transplantation: no adverse effect of low-dose fluconazole prophylaxis on incidence and outcome. [Bone Marrow Transplant. 2001]
Candida glabrata and Candida krusei fungemia after high-risk allogeneic marrow transplantation: no adverse effect of low-dose fluconazole prophylaxis on incidence and outcome.
Safdar A, van Rhee F, Henslee-Downey JP, Singhal S, Mehta J. Bone Marrow Transplant. 2001 Nov; 28(9):873-8.
A case of fungemia due to Candida krusei. [Nihon Ishinkin Gakkai Zasshi. ...]
A case of fungemia due to Candida krusei.
Mori T, Inamori K, Matsumura M, Oguri T, Oshimi K. Nihon Ishinkin Gakkai Zasshi. 1999; 40(1):15-20.

See reviews... See all...

Cited by 11 PubMed Central articles

Isolation, identification, and carriage of candidal species in PHLAs and their correlation with immunological status in cases with and without HAART. [J Oral Maxillofac Pathol. 2012]
Isolation, identification, and carriage of candidal species in PHLAs and their correlation with immunological status in cases with and without HAART.
Kantheti LP, Reddy B, Ravikumar S, Anuradha Ch, Chandrasekhar P, Rajeswari MR. J Oral Maxillofac Pathol. 2012 Jan; 16(1):38-44.
In vitro activity of nystatin compared with those of liposomal nystatin, amphotericin B, and fluconazole against clinical Candida isolates. [J Clin Microbiol. 2002]
In vitro activity of nystatin compared with those of liposomal nystatin, amphotericin B, and fluconazole against clinical Candida isolates.
Arikan S, Ostrosky-Zeichner L, Lozano-Chiu M, Paetznick V, Gordon D, Wallace T, Rex JH. J Clin Microbiol. 2002 Apr; 40(4):1406-12.
Review Antifungal prophylaxis during neutropenia and immunodeficiency. [Clin Microbiol Rev. 1997]
Review Antifungal prophylaxis during neutropenia and immunodeficiency.
Lortholary O, Dupont B. Clin Microbiol Rev. 1997 Jul; 10(3):477-504.

See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Compound (MeSH Keyword)
PubChem chemical compound records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Invasive infections due to Candida krusei: report of ten cases of fungemia that ...
Invasive infections due to Candida krusei: report of ten cases of fungemia that include three cases of endophthalmitis.
Clin Infect Dis. 1992 Feb ;14(2):472-8.

PubMed
Local fever illness classifications: implications for home management of malaria...
Local fever illness classifications: implications for home management of malaria strategies.
Trop Med Int Health. 2004 Nov ;9(11):1191-9.

PubMed
New evidence for parallel evolution of colour patterns in Malagasy poison frogs ...
New evidence for parallel evolution of colour patterns in Malagasy poison frogs (Mantella).
Mol Ecol. 2004 Dec ;13(12):3763-74.

PubMed
Group A streptococcal meningitis.
Group A streptococcal meningitis.
Clin Infect Dis. 1992 Feb ;14(2):418-21.

PubMed
Multicomponent individualized smoking cessation intervention for patients with l...
Multicomponent individualized smoking cessation intervention for patients with lung disease.
J Adv Nurs. 2004 Dec ;48(6):594-604.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: