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Physiology (Bethesda). 2004 Dec;19:348-54.

Common cues in vascular and axon guidance.

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  • 1Division of Molecular Angiogenesis, Institute for Cancer Research and Treatment, Department of Oncological Sciences, University of Torino School of Medicine, 10060 Candiolo (TO), Italy.


Blood vessels and nerves are structured in architecturally similar organ systems and show functional relationships. Indeed, vascular and neuronal cells are guided in their journey throughout the body by the same attractive and repulsive factors that respectively activate and inhibit the function of integrin-adhesive receptors.

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