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    Bioorg Med Chem Lett. 2004 Dec 20;14(24):5997-6000.

    Isoxazole-3-hydroxamic acid derivatives as peptide deformylase inhibitors and potential antibacterial agents.

    Calí P, Naerum L, Mukhija S, Hjelmencrantz A.

    Source

    Combio A/S, Vesterbrogade 188, DK-1800 Frederiksberg C, Denmark. pca@combio.biz

    Erratum in

    • Bioorg Med Chem Lett. 2005 May 2;15(9):2421.

    Abstract

    A series of isoxazole-3-hydroxamic acid derivatives has been identified as a new class of small, nonpeptidic inhibitors of peptide deformylase (PDF). The synthesis, enzyme inhibition and preliminary investigation of the binding mode of this potential antibacterial compounds are reported.

    PMID:
    15546716
    [PubMed - indexed for MEDLINE]

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