Display Settings:

Format

Send to:

Choose Destination
Neuron. 2004 Nov 18;44(4):581-4.

Ensemble dynamics of hippocampal regions CA3 and CA1.

Author information

  • 1Department of Neurosciences, University of New Mexico HSC, Albuquerque, NM 87131, USA. jguzowski@salud.unm.edu

Abstract

Computational models based on hippocampal connectivity have proposed that CA3 is uniquely positioned as an autoassociative memory network, capable of performing the competing functions of pattern completion and pattern separation. Recently, three independent studies, two using parallel neurophysiological recording methods and one using immediate-early gene imaging, have examined the responses of CA3 and CA1 ensembles to alterations of environmental context in rats. The results provide converging evidence that CA3 is capable of performing nonlinear transformations of sensory input patterns, whereas CA1 may represent changes in input in a more linear fashion.

PMID:
15541306
[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk