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Am J Cardiol. 2004 Nov 15;94(10):1322-5.

Association between exercise capacity and left ventricular geometry in overweight patients with mild systemic hypertension.

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  • 1Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA.


The purpose of this study was to determine the relation between left ventricular (LV) geometry and exercise capacity in unmedicated, hypertensive patients. Analysis of the data revealed peak oxygen consumption (ml kg(-1) min(-1)) for concentric hypertrophy (corrected mean +/- SE 23.5 +/- 1.2) was significantly less (F = 3.68, p <0.02) than the concentric remodeling (28.1 +/- 1.2) and normal (27.3 +/- 0.6) geometries. The LV geometric pattern was found to be associated with exercise capacity in unmedicated, hypertensive patients, such that patients with concentric hypertrophy showed reduced capacity.

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