Prevalence of porcine circovirus type 2 in aborted fetuses and stillborn piglets

Vet Rec. 2004 Oct 16;155(16):489-92. doi: 10.1136/vr.155.16.489.

Abstract

A retrospective study of natural cases of abortion, recorded between October 2000 and September 2002, was made to determine the prevalence of abortions associated with porcine circovirus type 2 (PCV-2). The virus was detected by PCR, immunohistochemistry and in situ hybridisation. A total of 46 (13.1 per cent) of 350 aborted fetuses and stillborn piglets were positive for PCV-2 by PCR, and the virus was detected in fetuses at all stages of gestation. Viral antigen was detected in macrophages from the aborted fetuses and stillborn piglets by immunohistochemistry, and viral DNA was detected by in situ hybridisation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aborted Fetus / virology
  • Abortion, Veterinary / pathology
  • Abortion, Veterinary / virology*
  • Animals
  • Circoviridae Infections / epidemiology
  • Circoviridae Infections / veterinary*
  • Circovirus / isolation & purification*
  • DNA, Viral / analysis
  • Female
  • Fetal Death / pathology
  • Fetal Death / veterinary
  • Fetal Death / virology
  • Immunohistochemistry / veterinary
  • In Situ Hybridization / veterinary
  • Polymerase Chain Reaction / veterinary
  • Pregnancy
  • Retrospective Studies
  • Swine
  • Swine Diseases / epidemiology*
  • United Kingdom / epidemiology

Substances

  • DNA, Viral