Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Genome Res. 2004 Nov;14(11):2308-18.

Global analysis of transcript and protein levels across the Plasmodium falciparum life cycle.

Author information

  • 1Department of Cell Biology ICND202, the Scripps Research Institute, La Jolla, California 92037, USA.

Abstract

To investigate the role of post-transcriptional controls in the regulation of protein expression for the malaria parasite, Plasmodium falciparum, we have compared mRNA transcript and protein abundance levels for seven different stages of the parasite life cycle. A moderately high positive relationship between mRNA and protein abundance was observed for these stages; the most common discrepancy was a delay between mRNA and protein accumulation. Potentially post-transcriptionally regulated genes are identified, and families of functionally related genes were observed to share similar patterns of mRNA and protein accumulation.

PMID:
15520293
[PubMed - indexed for MEDLINE]
PMCID:
PMC525690
Free PMC Article

Images from this publication.See all images (3)Free text

Figure 1.
Figure 2.
Figure 3.
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Write to the Help Desk