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Bioinformatics. 2005 Mar;21(6):829-31. Epub 2004 Oct 28.

GOChase: correcting errors from Gene Ontology-based annotations for gene products.

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  • 1Seoul National University Biomedical Informatics (SNUBI), Seoul National University College of Medicine, Seoul 110-799, Korea.

Abstract

SUMMARY:

The Gene Ontology (GO) is a controlled biological vocabulary that provides three structured networks of terms to describe biological processes, cellular components and molecular functions. Many databases of gene products are annotated using the GO vocabularies. We found that some GO-updating operations are not easily traceable by the current biological databases and GO browsers. Consequently, numerous annotation errors arise and are propagated throughout biological databases and GO-based high-level analyses. GOChase is a set of web-based utilities to detect and correct the errors in GO-based annotations.

PMID:
15513987
[PubMed - indexed for MEDLINE]
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