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Laterality. 1999 Jul;4(3):265-86.

Handedness in twins: a meta-analysis.

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  • 1Department of Neurology, UCLA School of Medicine, Los Angeles, CA 90095, USA.


In the largest meta-analysis of twins and singletons conducted to date we have found a higher incidence of left-handedness in twins compared to singletons. Our analysis revealed no difference in the frequency of left-handedness among monozygotic versus dizygotic twins. However, identical twins were more likely to be concordant for hand preference than non-identical twins, which is consistent with a genetic model of handedness. Prior analyses have not revealed these findings consistently, and this has led to a number of conflicting models of handedness.

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