Warning: The NCBI web site requires JavaScript to function. more...
Generate a file for use with external citation management software.
University of Arizona, Tucson, Arizona 85724, USA. egerner@azcc.arizona.edu
The amino-acid-derived polyamines have long been associated with cell growth and cancer, and specific oncogenes and tumour-suppressor genes regulate polyamine metabolism. Inhibition of polyamine synthesis has proven to be generally ineffective as an anticancer strategy in clinical trials, but it is a potent cancer chemoprevention strategy in preclinical studies. Clinical trials, with well-defined goals, are now underway to evaluate the chemopreventive efficacy of inhibitors of polyamine synthesis in a range of tissues.
Your browsing activity is empty.
Activity recording is turned off.
Turn recording back on