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J Virol. 2004 Nov;78(22):12709-11.

Seminal fluid enhances replication of human T-cell leukemia virus type 1: implications for sexual transmission.

Author information

  • 1Department of Pediatrics, Nagasaki University Hospital, Nagasaki 852-8501, Japan.

Abstract

Seminal fluid enhanced human T-cell leukemia virus type 1 (HTLV-1) infection by transactivating the HTLV-1 long terminal repeat promoter, which is chromosomally integrated in a cell-type-dependent manner. Our data may indicate a potential role for seminal fluid in the sexual transmission of HTLV-1 and imply complex features of regulation of HTLV-1 expression.

PMID:
15507662
[PubMed - indexed for MEDLINE]
PMCID:
PMC525095
Free PMC Article

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