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Expert Rev Cardiovasc Ther. 2004 Nov;2(6):877-89.

Recent advances in the secondary prevention of coronary heart disease.

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  • 1Wingate University School of Pharmacy, Campus Box 3087, Wingate, NC 28174 0157, USA. aveverka@wingate.edu.

Abstract

Current practice guidelines provide recommendations for the secondary prevention of coronary heart disease. Following the publication of clinical trials in recent years, this review will highlight some controversial issues: the role of angiotensin and aldosterone antagonists after acute myocardial infarction; the effects of angiotensin-converting enzyme inhibitors in patients with stable coronary heart disease and preserved left ventricular ejection fraction; high-intensity lowering of low-density lipoprotein cholesterol; use of 3-hydroxy-3-methyl-glutaryl coenzyme A reductase inhibitors in the elderly; and the targeting of high-density lipoprotein cholesterol with niacin.

PMID:
15500433
[PubMed - indexed for MEDLINE]
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