Clin Infect Dis. 2004 Nov 1;39(9):1380-4. Epub 2004 Oct 11.

Trends in AIDS-defining and non-AIDS-defining malignancies among HIV-infected patients: 1989-2002.

Bedimo R, Chen RY, Accortt NA, Raper JL, Linn C, Allison JJ, Dubay J, Saag MS, Hoesley CJ.

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University of Alabama at Birmingham, USA. roger.bedimo@med.va.gov

Abstract

In a comparison of rates of acquired immunodeficiency syndrome (AIDS)-defining malignancies (ADMs) for 1989-1996 versus 1997-2002, we found a decrease in ADMs (rate ratio, 0.31; P<.0001) and a significant increase in non-AIDS-defining malignancies (non-ADMs; rate ratio, 10.87; P<.0002). The mean CD4 cell count was lower among patients with ADMs than among those with non-ADMs. A longer duration of survival during highly active antiretroviral therapy might explain the increasing incidence of non-ADMs.

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Clin Infect Dis. 2005 Jul 1;41(1):124-6; author reply 126-7.

PMID:: 15494916; [PubMed - indexed for MEDLINE]

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