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Int J Med Microbiol. 2004 Sep;294(2-3):133-9.

Helicobacter pylori: recombination, population structure and human migrations.

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  • 1Institut für Medizinische Mikrobiologie und Krankenhaushygiene, Medizinische Hochschule Hannover, Carl-Neuberg-Str 1, D-30625 Hannover, Germany.


Helicobacter pylori shows extensive genetic diversity and variability due to frequent intraspecific recombination during mixed infection. In the last years, modern genetic and genomic technology as well as cutting-edge population genetic analysis have been used to investigate the population structure and genetic variability of this pathogen. This review article summarizes recent developments in this rapidly moving field.

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