Trends Biotechnol. 2004 Nov;22(11):552-5.

GenCompass: a universal system for analysing gene expression for any genome.

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Department of Molecular Biophysics and Biochemistry, Yale University, PO Box 208114, New Haven, CT 06520-8114, USA. nicholas.luscombe@yale.edu

Abstract

Microarrays have become indispensable tools for studying the gene expression of particular organisms on a genomic scale. However, despite its widespread use, there are several draw-backs to the current technology. First, it requires prior knowledge of the DNA sequence encoded in the organism of interest, and second, chips must be designed specifically for each genome, greatly increasing the initial cost incurred in manufacturing the arrays.

PMID:: 15491796; [PubMed - indexed for MEDLINE]

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