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    Int J Parasitol. 2004 Oct;34(11):1265-71.

    Expressed sequence tag (EST) analysis of Gregarine gametocyst development.

    Omoto CK, Toso M, Tang K, Sibley LD.

    Source

    School of Biological Sciences, Washington State University, Pullman, WA 99164-4236, USA. omoto@wsu.edu

    Abstract

    Gregarines are protozoan parasites of invertebrates in the phylum Apicomplexa. We employed an expressed sequence tag strategy in order to dissect the molecular processes of sexual or gametocyst development of gregarines. Expressed sequence tags provide a rapid way to identify genes, particularly in organisms for which we have very little molecular information. Analysis of approximately 1800 expressed sequence tags from the gametocyst stage revealed highly expressed genes related to cell division and differentiation. Evidence was found for the role of degradation and recycling in gametocyst development. Numerous additional genes uncovered by expressed sequence tag sequencing should provide valuable tools to investigate gametocyst development as well as for molecular phylogenetics, and comparative genomics in this important group of parasites.

    PMID:
    15491589
    [PubMed - indexed for MEDLINE]

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      Related information

      • Related Citations
        Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
      • EST
        Expressed Sequence Tag (EST) nucleotide sequence records reported in the current articles.
      • Taxonomy via GenBank
        Taxonomy records associated with the current articles through taxonomic information on related molecular database records (Nucleotide, Protein, Gene, SNP, Structure).
      • Cited in PMC
        Full-text articles in the PubMed Central Database that cite the current articles.

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