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Mol Cell Biol. 1992 Apr;12(4):1805-14.

Measurements of excision repair tracts formed during meiotic recombination in Saccharomyces cerevisiae.

Author information

  • 1Department of Biology, University of North Carolina, Chapel Hill 27599-3280.

Abstract

During meiotic recombination in the yeast Saccharomyces cerevisiae, heteroduplexes are formed at a high frequency between HIS4 genes located on homologous chromosomes. Using mutant alleles of the HIS4 gene that result in poorly repaired mismatches in heteroduplex DNA, we find that heteroduplexes often span a distance of 1.8 kb. In addition, we show that about one-third of the repair tracts initiated at well-repaired mismatches extend 900 bp.

PMID:
1549127
[PubMed - indexed for MEDLINE]
PMCID:
PMC369624
Free PMC Article
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