Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Vet Hum Toxicol. 2004 Oct;46(5):282-4.

Life-threatening isopropyl alcohol intoxication: is hemodialysis really necessary?

Author information

  • 1Intensive Care Unit. Hospital Clinic of Barcelona, Carrer Villarroel 170, 08036 Barcelona, Spain.

Abstract

Isopropyl alcohol (IPA) is widely used in industrial and home-cleaning products, easily available to general public and inexpensive: intoxications can occur unintentionally, in suicide attempts or by alcohol abusers as a substitute for ethanol. Symptoms involve the gastrointestinal tract, central nervous system and at high doses cardiovascular manifestations may appear. Ketonemia, ketonuria without hyperglicemia or acidosis and elevated osmol gap are common laboratory findings. Mortality and morbidity is low, but some fatal cases have been reported in patients in deep coma and especially those with hypotension. We present a life-threatening intoxication, with deep coma and hypotension, treated successfully with hemodialysis. Whether hemodialysis must always be performed is a controversial question. Our opinion is hemodialysis is not needed, even in life-threatening situations. Arguments about this opinion are presented.

PMID:
15487656
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Loading ...
    Write to the Help Desk